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Symposia Information
The 19th Annual Symposium organized by the Botulinum Research Center at the Institute of Advanced Sciences, Dartmouth, MA
This year's 19th Annual Botulinum Research Center Symposium will be held August 13-15, 2025, in New Bedford, MA
For virtual attendees, please use the Zoom meeting link below:
us02web.zoom.us/j/89984368528?pwd=XnQx4Kc9FnViccRquhKNrIlNq3kaac.1#success *
Wednesday, August 13, 2025 [US - Eastern Standard Time]
1 - 4 PM Attendees’ Arrival and Hotel Check-In
4:00 PM Delegate Registration and Opening Assembly, Wamsutta Club, 427 County Street, New Bedford, MA, USA
6:00 PM Dinner, Networking, and Evening Entertainment
Magic Show – Timothy Su, Department of Chemistry and Biochemistry, University of Massachusetts Dartmouth, USA
Lab Concert – John Bogdan, Valaria Technical Consultants/CYGNOS Biotech, Miami, FL, USA (Guitar) & Rishi Singh (Guitar)
Thursday, August 14, 2025 [Wamsutta Club, 1st Floor Conference Room]
8:00 AM Delegate Registration and Continental Breakfast
9:00 AM Introduction – Bal Ram Singh, National Botulinum Research Center, Institute of Advanced Sciences, Dartmouth, MA, USA
Session I
Session Chair – Eric Johnson, Retired Professor, University of Wisconsin, Madison, WI, USA
9:15 AM Inaugural Symposium Speech – The Botulism Spectrum: Surprising Insights from Stanford Research in the 1920s - Jane Talkington, Bradley University, Peoria, IL, USA; author of Recognizing Botulism: New Insights from Old Narratives
10:00 AM Q & A
10:15 AM Morning Break
Session II
Session Chair – Klaus Fink, MERZ, Germany
10:30 AM Synergistic Effects of 3, 4 – DAP and Antitoxin in Treatment of BoNT/A Poisoning – Patrick McNutt, Wake Forest University School of Medicine, Winston-Salem, NC, USA
11:00 AM Identification and Characterization of Botulinum Neurotoxin-like Toxins – Min Dong, Harvard Medical School, Boston, MA, USA
11:30 AM Noncanonical Glial Responses to Different Structural and Compositional Variants of Botulinum Neurotoxin – Ghuncha Ambrin, University of California San Diego, La Jolla, CA, USA
12:00 PM Case Studies on Macular Disease – Gary Borodic, Harvard Medical School, Boston, MA, USA
12:25 PM Symposium Luncheon
Session III
Session Chair – Karen Bunting, IPSEN BioInnovation Ltd., UK
1:00 PM Lifetime Achievement Award Speech – Botulinum Neurotoxin: A Lifelong Attempt to Understand Its Mysteries and Elegance, Michael Adler, US Army Medical Research Institute of Chemical Defense, Aberdeen Proving Ground, MD, USA
2:00 PM Group Photo
2:15 PM Poster Session, Intermission, and Open Networking
3:00 PM Glass Museum Visit (sign up available at registration)
6:00 PM Informal Dinner and Digital Experience Sharing, Institute of Advanced Sciences Conference Room, 78-520 Faunce Corner Mall Road, Dartmouth, MA, USA (transportation and sign up available at registration)
7:00 PM Dinner Speech – History of the First FDA-Approved Batch of Botox with All the Trials and Tribulations, Eric Johnson, Retired Professor, University of Wisconsin, Madison, WI, USA
Friday, August 15, 2025 [Wamsutta Club, 1st Floor Conference Room]
7:30 AM BRC Board of Advisors Meeting
8:00 AM Breakfast
Session IV
Session Chair – Michael Adler, US Army Medical Research Institute of Chemical Defense, Aberdeen Proving Ground, MD, USA
8:30 AM Dr. B.R. DasGupta Memorial Lecture – Small Molecule Inhibitors for the Treatment of Botulinum Intoxication, Kim Janda, Scripps Research, La Jolla, CA, USA
9:15 AM Q & A
9:30 AM Botulinum Neurotoxin for Tremor Syndromes – Roopa Ranjan, All India Institute of Medical Sciences, New Delhi, India
10:00 AM Morning Break
Session V
Session Chair – Shuowei Cai, University of Massachusetts Dartmouth, MA, USA
10:15 AM Clostridial Proteins: Unlocking Therapeutical Potential from Bacterial Proteins – Raj Kumar, National Botulinum Research Center, Institute of Advanced Sciences, Dartmouth, MA, USA
10:40 AM Preeclampsia and the Brain: A New Era – Surendra Sharma, University of Texas Medical Branch, Galveston, TX, USA
11:05 AM Modeling SBMA Using Isogenic hiPSC-Derived Motor Neurons and Neural Stem Cells – Xia Feng, Mass General Hospital, Boston, MA, USA
11:30 AM PVX, a Host-Targeting Broad-Spectrum Antiviral Therapeutic Derived from Cobra Venom Toxin – John Bogdan, CYGNOS Biotech, Miami, FL, USA, and Valaria Technical Consultants, LLC.
11:55 AM Aesthetic Uses of BoNT – Andy Ress, Liv Plastic Surgery, Boca Raton, FL, USA
12:20 PM Accelerated Reversal of BoNT/A-Induced Paralysis via Super Therapeutic Doses of 3, 4-Diaminopyridine – Travis Wentz, Wake Forest University School of Medicine, Winston-Salem, NC, USA
12:45 PM Symposium Luncheon
Session VI
Session Chair – Robert Hall, Former Program Manager, National Institutes of Health, Rockville, MD, USA
1:30 PM Panel Discussion: Unexplored Aspects of Botulinum Neurotoxin
Karen Bunting – IPSEN BioInnovations Ltd., UK
Klaus Fink – MERZ, DE
Lance Steward – AbbVie/Allergan, USA
John Bogdan – CYGNOS Biotech, USA
Min Dong – Harvard Medical School, USA
2:30 PM Conclusion & Networking, and Departure
Should you have any issues, contact Keri@INADS.org & MLindo@INADS.org for assistance.
Start Date: 13-08-2025
End Date: 15-08-2025
Fifth - Final Announcement 2025 BRC - Event Information & Registration18th Annual Botulinum Research Center Symposium
The 18th annual symposium organized by the Botulinum Research Center at the Institute of Advanced Sciences, Dartmouth, MA
Program:
Wednesday, August 14, 2024, 7 PM (Eastern Standard Time, US)
- 1 to 4 PM - Arrival and check-in at hotels of general delegates
- 4:00 PM - Registration and welcome, Wamsutta Club, 427 County Street, New Bedford, MA
- 6:00 PM - Social, entertainment, and dinner
- Magic by Timothy Su
- Music by John Bogdan
Thursday, August 15, 2024, (Eastern Standard Time, US)
- 8:00 AM - Registration and continental breakfast
- 9:00 AM - Introduction by Bal Ram Singh, Botulinum Research Center
Session I - Session Chair - Dirk Dressler, Medizinische Hochschule Hannover, Germany
- 9:30 AM - Inaugural Symposium Speech by Frederic Meunier, Queensland Brain Institute and School of Biomedical Sciences, The University of Queensland, St. Lucia campus, QLD, 4072, Australia
- Botulinum neurotoxin type A hijacks polysialogangliside-Synaptotamin1-SV2 surface nanocluster to sneak in synaptic vesicles
- 10:15 AM - Q & A
- 10:30 AM - Coffee/tea break
Session II - Session Chair - Karen Bunting, IPSEN Bioinnovations Ltd, UK
- 11:00 AM - Evaluating combination treatment strategies for BoNT/A poisoning by Patrick McNutt, Wake Forest University School of Medicine, Winston-Salem, NC, USA
- 11:30 AM - Evaluation of the mass spectroscopy assay for botulinum toxins by Eric Johnson, Professor (Retired), Madison, WI, USA
- 12:00 PM - Intermission
- 12:15 PM - Lunch Banquet
Session III - Session Chair - Klaus Fink, MERZ Germany
- 1:00 PM - Lifetime Achievement Award Speech by James Marks, Professor Emeritus, Department of Anesthesiology, University of California, San Francisco, CA, USA
- Lessons learned and friendships made engineering botulinum antibodies
- 2:00 PM - Group photo
- 2:15 PM - Break, social, free mingling, and meetings
- 3:00 PM - Whaling Museum and area walking tour
- 6:00 PM - Informal dinner at Wamsutta Club
- Sharing of online experiences
- 7:00 PM - Dinner speech by Gary Borodic, Harvard Medical School, USA
- Botulinum therapy for macular disease
Friday, August 16, 2024, (Eastern Standard Time, US)
- 7:30 AM - BRC Board of Advisors meeting
- 8:00 AM - Breakfast
Session IV - Session Chair - Dr. Michael Adler, US Army Medical Research Institute of Chemical Defense
- 8:30 AM - Dr. B.R. DasGupta Memorial Lecture by Joe Barbieri, Medical College of Wisconsin, Milwaukee, USA
- Intracellular trafficking of botulinum neurotoxin light chain/A1 to cleave SNAP-25
- 9:15 AM - Q & A
- 9:30 AM - A novel platform for therapeutic utility of clostridial proteins by Raj Kumar, Botulinum Research Center, Institute of Advanced Sciences, Dartmouth, MA, USA
- 10:00 AM - Coffee/tea break
Session V - Session Chair - Shuowai Cai, University of Massachusetts Dartmouth, USA
- 10:15 AM - Immunogenicity of botulinum toxin drugs: What do we know? by Dirk Dressler, Medizinische Hochschule Hannover, Germany
- 10:45 AM - Growing product development with government funding by John Bogdan, Valaria Technical Consultants, LLC, Westminster, MD, USA
- 11:15 AM - From novel to known: Exploring the landscape of botulinum toxin homologs by Travis Wentz, Wake Forest Institute of Regenerative Medicine, Salem, NC, USA
- 11:45 AM - BoNT/DC blocks melanin production by Birgitte Sondergaard, Abbvie/Allergan, USA
- 12:15 PM - Lunch
Session VI - Session Chair - John Bogdan, Valaria Technical Consultants, LLC, Westminster, MD, USA
- 1:15 PM - Panel discussion: Medical Avenues of BoNT Therapeutics
- Karen Bunting, IPSEN Bioinnovations Ltd, UK
- Klaus Fink, MERZ, Germany
- Birgitte Sondergaard, Abbvie/Allergan, USA
- Frederic Meunier, University of Queensland
- 2:15 PM - Symposium conclusion, lunch, networking, and departure
Venue: Wamsutta Club, New Bedford, MA & Zoom Meeting Room (hybrid)
Event Announcement & Registration:
- Please use the link above to register for this event. Only registered attendees will receive the virtual meeting link (for those not in person). This will allow the meeting coordinators to know how many attendees are expected and to plan accordingly. Thank you.
Hotel Information:
The Fairfield Inn is within walking distance from the Wamsutta Club. Transportation will be provided from the Residence Inn and Best Western. Please let us know if you will be requiring transportation to and from the event.
- Best Western - New Bedford/Dartmouth, MA
- Phone Number: (508) 717-0424
- Residence Inn - New Bedford/Dartmouth, MA > Website Link to Book
- Phone Number: (508) 984-5858
- Fairfield Inn & Suites - New Bedford, MA > Website Link to Book
- Phone Number: (774) 634-2000
**Please email Keri@inads.org with any questions or issues**
Start Date: 14-08-2024
End Date: 16-08-2024
| Event Registration | : | |
| Alternate Registration Link | : | |
| First Announcement | : |
First Announcement for the 18th Annual Botulinum Research Center Symposium to be held on August 14-16, 2024. |
| Second Announcement | : |
Second Announcement for the 18th Annual Botulinum Research Center Symposium |
| Third Announcement | : |
Third Announcement for the 18th Annual Botulinum Research Center Symposium |
| Fourth Announcement - 2024 BRC | : |
Fourth Announcement for the 18th Annual Botulinum Research Center Symposium |
| Fifth and Final Announcement - Program | : |
Fifth and Final Announcement & Program for the 18th Annual Botulinum Research Center Symposium |
17th Annual Botulinum Research Symposium, July 19-21, 2023
The 17th annual symposium organized by the Botulinum Research Center at the Institute of Advanced Sciences, Dartmouth, MA
Start Date: 19-07-2023
End Date: 21-07-2023
| Final Announcement | : |
Fourth & Final Announcement 17th Annual Botulinum Research Symposium, July 19-21, 2023 |
16th Annual Botulinum Research Symposium, August 17-18, 2022
The 16th annual symposium organized by the Botulinum Research Center at the Institute of Advanced Sciences, Dartmouth, MA.
Start Date: 17-08-2022
End Date: 18-08-2022
| Final Announcement | : |
Third & Final Announcement 16th Annual Botulinum Research Symposium, August 17-18, 2022 |
15th Annual Botulinum Research Symposium, August 18-19, 2021
The 15th annual symposium organized by the Botulinum Research Center at the Institute of Advanced Sciences, Dartmouth, MA.
Start Date: 18-08-2021
End Date: 19-08-2021
14th Annual Botulinum Research Center Symposium, August 20-21, 2020
The 14th annual symposium organized by the Botulinum Research Center at the Institute of Advanced Sciences, Dartmouth, MA
Start Date: 20-08-2020
End Date: 21-08-2020
Final Announcement13th Annual Botulinum Research Symposium, August 14-16, 2019
The 13th annual symposium organized by the Botulinum Research Center at the Institute of Advanced Sciences, Dartmouth, MA
Start Date: 14-08-2019
End Date: 16-08-2019
| Hotel information | : |
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| 1st ANNOUNCEMENT | : |
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| 2nd Announcement | : |
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| Tentative Program | : |
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| Final Program | : |
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12th Annual Botulinum Research Symposium, August 15-17, 2018
The 12th annual symposium organized by the Botulinum Research Center at the Institute of Advanced Sciences, Dartmouth, MA.
Start Date: 15-08-2018
End Date: 17-08-2018
| Hotel Details | : |
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| 1st ANNOUNCEMENT | : |
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| 2nd Announcement | : |
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| 3rd Announcement | : |
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| Final Program Schedule | : |
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11th Annual Botulinum Research Symposium, August 16-18, 2017
The 11th annual symposium organized by the Botulinum Research Center at the Institute of Advanced Sciences, Dartmouth, MA.
Start Date: 16-08-2017
End Date: 18-08-2017
| 1st ANNOUNCEMENT | : |
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| 2nd Announcement | : |
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| Hotel Details | : |
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| Tentative Program Schedule | : |
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10th Annual Botulinum Research Symposium
The 10th annual symposium organized by the Botulinum Research Center at the Institute of Advanced Sciences, Dartmouth, MA.
Start Date: 17-08-2016
End Date: 19-08-2016
| Final Program Schedule (Revised) | : |
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| 3rd ANNOUNCEMENT | : |
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| 2nd ANNOUNCEMENT | : |
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| VENUE | : |
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| HOTEL INFORMATION | : |
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| BOARD OF ADVISORS | : |
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| 1st ANNOUNCEMENT | : |
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9th annual Botulinum Research Center Symposium, August 12-14, 2015
The 9th Annual Botulinum Research Symposium organized by Botulinum Research Center at the Institute of Advanced Sciences, August 12-14, 2015, Dartmouth, MA
Start Date: 12-08-2015
End Date: 14-08-2015
View moreSymposium 2014
The 8th Annual Botulinum Research Symposium, 2014 organized by the Botulinum Research Center at the Institute of Advanced Sciences, August 13-15, 2014, Dartmouth, MA
Start Date: 13-08-2014
End Date: 15-08-2014
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The 7th Annual Botulinum Research Symposium, 2013 organized by the Botulinum Research Center at UMass Dartmouth on August 14-16, 2013.
Start Date: 14-08-2019
End Date: 16-08-2019
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The 6th Annual Botulinum Research Symposium, 2012 at UMass Dartmouth on August 16-17, 2012.
Start Date: 16-08-2012
End Date: 17-08-2012
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The 5th Annual Botulinum Research Symposium, 2011 organized by Botulinum Research Center at the Institute of Advanced Sciences, August 17-19, 2011, Dartmouth, MA
Start Date: 17-08-2011
End Date: 19-08-2011
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The 4th Annual Botulinum Research Symposium, 2010 organized by Botulinum Research Center at the Institute of Advanced Sciences, August 19-20, 2010, Dartmouth, MA
Start Date: 19-08-2010
End Date: 20-08-2010
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The 3rd Annual Botulinum Research Symposium, 2009 organized by Botulinum Research Center at the Institute of Advanced Sciences, August 20-21, 2009, Dartmouth, MA
Start Date: 20-08-2009
End Date: 21-08-2009
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The 2nd Annual Botulinum Research Symposium, 2008 organized by Botulinum Research Center at the Institute of Advanced Sciences, August 20-21, 2008, Dartmouth, MA
Start Date: 20-08-2008
End Date: 21-08-2008
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The 1st Annual Botulinum Research Symposium, 2007 organized by Botulinum Research Center at the Institute of Advanced Sciences, August 23-24, 2007 Dartmouth, MA
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End Date: 24-08-2007
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